| ROSSO✗ | Independiente Medellín vs Boyacá Chicó Colombia— Colombia | Colombia— Colombia | 2-01T: 2-0 |
| ROSSO✓ | Columbus vs LA GalaxyUSA | USA | 2-11T: 1-0 |
| ROSSO✗ | New York City FC vs CincinnatiUSA | USA | 4-41T: 2-1 |
| ROSSO✗ | New York RB vs DC UnitedUSA | USA | 4-4 |
| ROSSO✗ | Toronto vs Philadelphia UnionUSA | USA | 3-31T: 0-1 |
| ARANCIO✓ | Orlando City vs CharlotteUSA | USA | 4-11T: 1-1 |
| ROSSO✓ | Rhode Island vs Charleston Battery USA B— USA | USA B— USA | 4-01T: 0-0 |
| ROSSO✓ | Atlanta United vs New EnglandUSA | USA | 1-21T: 1-0 |
| ROSSO✗ | Pérez Zeledón vs Herediano Costa Rica— Costa Rica | Costa Rica— Costa Rica | 0-11T: 0-0 |
| ARANCIO✗ | Houston Dynamo vs San DiegoUSA | USA | 1-01T: 1-0 |
| ROSSO✗ | Dallas vs Minnesota UnitedUSA | USA | 0-11T: 0-1 |
| ARANCIO✗ | Atletico San Luis vs Santos LagunaMessico | Messico | 2-01T: 0-0 |
| ROSSO✗ | Mazatlán vs TolucaMessico | Messico | 4-31T: 0-1 |
| ROSSO✗ | Atlas vs TigresMessico | Messico | 0-01T: 0-0 |
| ROSSO✓ | Fortaleza vs América de CaliColombia— Colombia | Colombia— Colombia | 1-21T: 0-1 |
| ARANCIO✗ | Real Salt Lake vs Inter MiamiUSA | USA | 0-21T: 0-0 |
| ARANCIO✗ | Oakland Roots vs Las Vegas LightsUSA B— USA | USA B— USA | 4-21T: 2-0 |
| ARANCIO✓ | Saprissa vs GuadalupeCosta Rica— Costa Rica | Costa Rica— Costa Rica | 5-01T: 1-0 |
| ROSSO✗ | SJ Earthquakes vs Austin FCUSA | USA | 5-11T: 0-1 |
| ROSSO✗ | Los Angeles FC vs Colorado RapidsUSA | USA | 0-01T: 0-0 |
| GIALLO✗ | Necaxa vs GuadalajaraMessico | Messico | 0-01T: 0-0 |
| ROSSO✓ | Tijuana vs PachucaMessico | Messico | 3-11T: 2-0 |
| ARANCIO✗ | Al Sharjah vs Al Wahda Emirati Arabi— Emirati Arabi | Emirati Arabi— Emirati Arabi | 0-21T: 0-1 |
| ARANCIO | Kalba vs Bani YasEmirati Arabi— Emirati Arabi | Emirati Arabi— Emirati Arabi | 16:00 |
| ARANCIO | Al Najma vs Al TaawounArabia Saudita | Arabia Saudita | 18:00 |
| GIALLO✓ | Randers vs FredericiaDanimarca | Danimarca | 2-21T: 1-2 |
| ARANCIO | Nordsjælland vs AGFDanimarca | Danimarca | 18:00 |
| ARANCIO✗ | Go Ahead Eagles vs AZOlanda | Olanda | 0-01T: 0-0 |
| ROSSO | Damac vs Al OkhdoudArabia Saudita | Arabia Saudita | 20:00 |
| ROSSO | Sønderjyske vs MidtjyllandDanimarca | Danimarca | 20:00 |
| ROSSO✗ | Rayo Vallecano vs Espanyol La Liga— Spagna | La Liga— Spagna | 1-01T: 0-0 |
| ARANCIO✗ | Wieczysta Kraków vs Polonia Bytom Polonia B— Polonia | Polonia B— Polonia | 4-31T: 0-2 |
| ROSSO✗ | Casa Pia vs BragaPortogallo | Portogallo | 0-11T: 0-1 |
| ROSSO✓ | Lommel vs RFC Liegi Belgio B— Belgio | Belgio B— Belgio | 3-01T: 2-0 |
| ROSSO✗ | Patro Eisden vs BeerschotBelgio B— Belgio | Belgio B— Belgio | 1-11T: 1-0 |
| ROSSO✗ | Stoccarda vs FriburgoCoppa di Germania | Coppa di Germania | 1-11T: 0-1 |
| ROSSO✗ | Salford City vs Bromley League Two— Inghilterra | League Two— Inghilterra | 2-01T: 0-0 |
| ARANCIO✗ | PSV vs PEC ZwolleOlanda | Olanda | 6-11T: 1-0 |
| ROSSO✗ | Real Oviedo vs VillarrealLa Liga— Spagna | La Liga— Spagna | 1-11T: 0-1 |
| ARANCIO✗ | Los Chankas vs Cienciano Peru— Perù | Peru— Perù | 1-01T: 0-0 |