| Rosso✗ | Independiente Medellín vs Boyacá Chicó Colombia— Colombia | Colombia— Colombia | 2-01T: 2-0 |
| Rosso✓ | Columbus vs LA GalaxyUSA (*) | USA (*) | 2-11T: 1-0 |
| Rosso✗ | New York City FC vs CincinnatiUSA (*) | USA (*) | 4-41T: 2-1 |
| Rosso✗ | New York Red Bulls vs DC UnitedUSA (*) | USA (*) | 4-4 |
| Rosso✗ | Toronto vs Philadelphia UnionUSA (*) | USA (*) | 3-31T: 0-1 |
| Arancio✓ | Orlando City vs CharlotteUSA (*) | USA (*) | 4-11T: 1-1 |
| Rosso✓ | Rhode Island vs Charleston Battery USA B— USA | USA B— USA | 4-01T: 0-0 |
| Rosso✓ | Atlanta United vs New England RevolutionUSA (*) | USA (*) | 1-21T: 1-0 |
| Rosso✗ | Pérez Zeledón vs Herediano Costa Rica— Costa Rica | Costa Rica— Costa Rica | 0-11T: 0-0 |
| Arancio✗ | Houston Dynamo vs San DiegoUSA (*) | USA (*) | 1-01T: 1-0 |
| Rosso✗ | Dallas vs Minnesota UnitedUSA (*) | USA (*) | 0-11T: 0-1 |
| Arancio✗ | Atletico San Luis vs Santos LagunaMessico (*) | Messico (*) | 2-01T: 0-0 |
| Rosso✗ | Mazatlán vs TolucaMessico (*) | Messico (*) | 4-31T: 0-1 |
| Rosso✗ | Atlas vs TigresMessico (*) | Messico (*) | 0-01T: 0-0 |
| Rosso✓ | Fortaleza vs América de CaliColombia— Colombia | Colombia— Colombia | 1-21T: 0-1 |
| Arancio✗ | Real Salt Lake vs Inter MiamiUSA (*) | USA (*) | 0-21T: 0-0 |
| Arancio✗ | Oakland Roots vs Las Vegas LightsUSA B— USA | USA B— USA | 4-21T: 2-0 |
| Arancio✓ | Saprissa vs GuadalupeCosta Rica— Costa Rica | Costa Rica— Costa Rica | 5-01T: 1-0 |
| Rosso✗ | San Jose Earthquakes vs Austin FCUSA (*) | USA (*) | 5-11T: 0-1 |
| Rosso✗ | Los Angeles FC vs Colorado RapidsUSA (*) | USA (*) | 0-01T: 0-0 |
| Giallo✗ | Necaxa vs GuadalajaraMessico (*) | Messico (*) | 0-01T: 0-0 |
| Rosso✓ | Tijuana vs PachucaMessico (*) | Messico (*) | 3-11T: 2-0 |
| Arancio✗ | Al Sharjah vs Al Wahda Emirati Arabi— Emirati Arabi | Emirati Arabi— Emirati Arabi | 0-21T: 0-1 |
| Arancio | Kalba vs Bani YasEmirati Arabi— Emirati Arabi | Emirati Arabi— Emirati Arabi | 16:00 |
| Arancio | Al Najma vs Al TaawounArabia Saudita (*) | Arabia Saudita (*) | 18:00 |
| Giallo✓ | Randers vs FredericiaDanimarca (*) | Danimarca (*) | 2-21T: 1-2 |
| Arancio | Nordsjælland vs AarhusDanimarca (*) | Danimarca (*) | 18:00 |
| Arancio✗ | Go Ahead Eagles vs AZOlanda (*) | Olanda (*) | 0-01T: 0-0 |
| Rosso | Damac vs Al OkhdoudArabia Saudita (*) | Arabia Saudita (*) | 20:00 |
| Rosso | Sønderjyske vs MidtjyllandDanimarca (*) | Danimarca (*) | 20:00 |
| Rosso✗ | Rayo Vallecano vs Espanyol La Liga (*)— Spagna | La Liga (*)— Spagna | 1-01T: 0-0 |
| Arancio✗ | Wieczysta Kraków vs Polonia Bytom Polonia B— Polonia | Polonia B— Polonia | 4-31T: 0-2 |
| Rosso✗ | Casa Pia vs BragaPortogallo (*) | Portogallo (*) | 0-11T: 0-1 |
| Rosso✓ | Lommel vs RFC Liegi Belgio B— Belgio | Belgio B— Belgio | 3-01T: 2-0 |
| Rosso✗ | Patro Eisden vs BeerschotBelgio B— Belgio | Belgio B— Belgio | 1-11T: 1-0 |
| Rosso✗ | Stoccarda vs FriburgoCoppa di Germania (*) | Coppa di Germania (*) | 1-11T: 0-1 |
| Rosso✗ | Salford City vs Bromley League Two (*)— Inghilterra | League Two (*)— Inghilterra | 2-01T: 0-0 |
| Arancio✗ | PSV Eindhoven vs PEC ZwolleOlanda (*) | Olanda (*) | 6-11T: 1-0 |
| Rosso✗ | Real Oviedo vs VillarrealLa Liga (*)— Spagna | La Liga (*)— Spagna | 1-11T: 0-1 |
| Arancio✗ | Los Chankas vs Cienciano Peru— Perù | Peru— Perù | 1-01T: 0-0 |